Contrary to prior data, this study shows that neither eosinophils nor STAT6-mediated IL-4/IL-13 signaling contribute ...

The guidelines support use of PPIs, dietary therapy, and biologics for EoE, and stress the importance of addressing both the inflammatory and fibrostenotic aspects of the disease.

For example, it might help to predict the potential of drugs (or related compounds) being developed for marketing, to trigger basophil activation. The fact that in this context the BAT does not ...

Eotaxin-3 together with IL-5, ultimately lead to eosinophils recruitment, activation, and degranulation. IL-4/IL-13 also promote DC activation, M2 macrophage polarization, IgE class switching by ...

1 Laboratory for Clinical Immunology and Molecular Genetics, University Clinic of Respiratory and Allergic Diseases Golnik, Golnik, Slovenia 2 Faculty of Pharmacy, University of Ljubljana, Ljubljana, ...

Whilst the steps for inflammation generally remain the same there are some other specialised leukocytes that are recruited when the pathogen is a parasite or a virus. Click on the hotspots in the ...

Fluorescence-activated cell sorting analysis also indicated an increase in the number of eosinophils in RS mice by two- to four-fold as compared to US mice. However, neutrophil, basophil ...

Dr. Annie Liu (Medicine): A 35-year-old woman was admitted to this hospital because of shortness of breath and edema in the legs. Eight weeks before the current presentation, the patient was ...