In addition, the suppression of this signature by ICS therapy and the reversal of the expression of this signature by cessation of ICS therapy reinforces the similarity of this COPD endotype to severe ...

The non-professional APCs found in the lung include AECs, ECs, fibroblasts, ILCs, Eosinophils, Interstitial cells, and Mast Cells. In the upcoming parts of this analysis, we will gather the newly ...

[37] This variant includes patients with stent thrombosis in whom thrombus harvesting and staining with hematoxylin–eosin and Giemsa reveals the presence of eosinophils and mast cells ...

Contrary to prior data, this study shows that neither eosinophils nor STAT6-mediated IL-4/IL-13 signaling contribute ...

Moreover, we found that FCER1, involved in mast cell activation, was upregulated in the SARS+ Mild group but significantly downregulated in the SARS+ Moderate/Severe group. In both SARS+ groups we ...

These factors can activate mast cells to release proinflammatory mediators and some of them, for example, histamine, tryptase and nerve growth factor, can stimulate sensory C-fibers. Since ...

In a report released yesterday, Sam Slutsky from LifeSci Capital maintained a Hold rating on Allakos (ALLK – Research Report), with a price ...

Leerink Partners analyst Thomas Smith has reiterated their neutral stance on ALLK stock, giving a Hold rating on January 27.Invest with ...

Low-grade inflammation was evaluated by counting cells, including intraepithelial lymphocytes (IELs), eosinophils and mast cells, and by determining the mRNA and protein expression of tumour necrosis ...

In recent years, scientific studies have revealed that mucosal mast cells (MMCs), which are immune cells that arise from bone marrow, are excessively produced and play a key role in the severity ...