Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic ...

Cell competition in epithelial tissue eliminates transformed cells expressing activated oncoproteins to maintain epithelial homeostasis. Although the process is now understood to be of mechanochemical ...

Colonic epithelium is situated above a layer of fibroblasts that provide supportive factors for stem cells at the crypt base and promote differentiation of cells in the upper crypt and luminal surface ...

Human Amniotic Epithelial Stem Cells is under clinical development by iCELL Biotechnology and currently in Phase I for Parkinson's Disease.

Scientists found that healthy women can carry genetic changes in their breast cells that are thought to be characteristic of ...

Inhibiting the HIF2 protein was found to promote repair processes in a mouse model of lung injury, and may be a strategy for ...

Objective We tested the ability of Notch pathway receptors Notch1 and Notch2 to regulate stem and epithelial cell homoeostasis in mouse and human gastric antral tissue. Design Mice were treated with ...

Corneal epithelial thickness increases and stromal thickness decreases appear to worsen symptoms of dry eye disease.

In mechanobiology, cells' forces have been considered fundamental to their enhanced function, including fast migration. But a ...

We investigated the functional role of autophagy in oesophageal epithelial cells (keratinocytes) exposed to the inflammatory EoE milieu. Design Functional consequences of genetic or pharmacological ...