Their study, published recently in Nature, focuses on what is known as the estrogen receptor, a protein linked in previous research to the development of roughly 70% of all breast tumors.
Breast cancer (BC) is one of the most common malignancies and the leading cause of cancer-related mortality in women. Androgen receptor (AR) is frequently expressed in diverse BC subtypes.
They further found that VDCC could trigger calcium mobilization, thereby inducing the activation of the insulin-like growth factor receptor (IGF-1R) and promoting cancer metastasis through the ...