Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...
Scientists have developed a groundbreaking approach using specially designed peptides to improve drug formulations. This innovative method significantly enhances anti-tumor efficacy. A team of ...
For example, if 0.5 per cent of the amino-groups remain unacylated after each coupling, then after one hundred stages the product will contain only 61 per cent of the required peptide, the ...