Objective: To test the hypothesis that once-daily treatment with fluticasone propionate is as effective as twice-daily treatment in children with well controlled asthma. Design: Multicentre ...

Introduction: The incidence of asthma exacerbations in patients receiving salmeterol/fluticasone propionate (Seretide™ or Advair ®) is low. However, when asthma control deteriorates ...

Recent evidence suggests that the short chain fatty acid propionate may play an important role in appetite regulation. We hypothesised that colonic delivery of propionate would increase peptide YY ...

The effect of both types of treatment can be assessed by measuring lung and systemic parameters. Treatment for two weeks with either oral prednisolone (30 mg/day), high dose fluticasone propionate ...

In addition, prior observational studies comparing budesonide and fluticasone analyzed short acting fluticasone propionate rather than the longer acting fluticasone furoate, which is found in ...

Spring is the most common time of the year for people to experience seasonal allergy symptoms. As the weather gets warmer and plants start to bloom, trees and grasses release pollen into the air, ...

Study: Short-chain fatty acid metabolites propionate and butyrate are unique ... Despite these findings, the precise mechanisms by which SCFAs regulate chromatin and gene expression remain unclear ...

New research identifies key cellular mechanism driving Alzheimer's disease. ScienceDaily . Retrieved January 14, 2025 from www.sciencedaily.com / releases / 2024 / 12 / 241223135051.htm ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

Here the authors investigate the underlying mechanisms in a mouse model of menopause and find that the loss of 17β-estradiol and progesterone enhanced susceptibility to senescence, extracellular ...

Background Exacerbations of chronic obstructive pulmonary disease (COPD) are characterised by increased dyspnoea, reduced quality of life and muscle weakness. Re-exacerbation and hospital admission ...

From Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Victoria, Australia (R.H.R.) Division of Endocrinology and Metabolism (E.D.A.), ...