G protein-coupled receptors (GPCRs), crucial for diverse physiological responses, have traditionally been investigated in ...
In a significant advancement for cancer research, a team of scientists from Max Planck Institute for Biology Tübingen, ...
Predators and prey in the ocean rely on chemical signals for survival, but this vital sensory mode can also be their Achilles ...
You have full access to this article via your institution. The binding of a peptide to a G protein- coupled receptor (GPCR), which elicits an increase in intracellular calcium, is a common ...
G-protein-coupled receptors (GPCRs) — which make up the largest and most diverse family of receptors in humans — are encoded by at least 800 distinct genes. Many GPCRs have functions in taste ...
A new protein antagonist design strategy shows promise against leukaemia by targeting important receptors to stop the proliferation of cancer cells. A new family of protein-based antagonists has been ...
Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors (GPCRs), proteins embedded in cell membranes that allow cells to communicate with ...
Materials and Process Simulation Center, California Institute of Technology, Pasadena, California 91125, United States ...
MetaVia Inc. (Nasdaq: MTVA), a clinical-stage biotechnology company focused on transforming cardiometabolic diseases, today announced that it is holding an Advisory Committee meeting today, at the 9th ...
Adhesion G protein-coupled receptors have a large extracellular region (shown in green and orange) that extends into space outside the cell. Almost 35% of drugs approved by the Food and Drug ...
DP2, as a G protein-coupled receptor, plays a crucial role in mediating allergic responses and inflammation. However, the clinical application of several DP2-targeted drugs remains limited.