高度近视在全球的患病率呈上升趋势，已成为严峻的健康挑战。高度近视性白内障作为高度近视最常见的并发症，发病年龄比年龄相关性白内障更早，严重影响患者工作期间的生活质量。由于晶状体核通常较硬，HMC 的手术干预难度较大，因此深入了解其发病机制对开发潜在治疗方法至关重要。

【导读】雌激素受体阳性（ER+）乳腺癌约占病例的 70%。靶向雌激素的内分泌疗法是 ER+ 乳腺癌的一线疗法。然而，约有一半的患者会对这些疗法产生耐药性，从而导致生存率降低。

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, P.R. China University of the Chinese ...

This study aimed to investigate the pharmacological activity and underlying MOA. Conclusion: ORes inhibits breast cancer cell growth by inducing ferroptosis through suppression of the ...

From the GO analysis, we screened the upregulated differentially expressed genes and identified key pathways, including mitophagy, autophagy, ferroptosis, apoptosis, nonalcoholic fatty liver disease ...