高度近视在全球的患病率呈上升趋势，已成为严峻的健康挑战。高度近视性白内障作为高度近视最常见的并发症，发病年龄比年龄相关性白内障更早，严重影响患者工作期间的生活质量。由于晶状体核通常较硬，HMC 的手术干预难度较大，因此深入了解其发病机制对开发潜在治疗方法至关重要。

Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China CAS Key Laboratory for ...

Martin-Sanchez confirmed the presence of the characteristics of ferroptosis in folate-induced mouse AKI models, which are lipid peroxidation and downregulation of GSH (Martin-Sanchez et al ... GR or ...

Erastin (ER), a ferroptosis inducer, kills tumor cells by generating and accumulating reactive oxygen species (ROS) within the cell, resulting in an iron-dependent oxidative damage-mediated ...

From the GO analysis, we screened the upregulated differentially expressed genes and identified key pathways, including mitophagy, autophagy, ferroptosis, apoptosis, nonalcoholic fatty liver disease ...