Mutations that disrupt the trpR gene lead to elevated production ... can once again bind to the operator/promoter, quickly turning off expression of the operon, returning expression to basal ...

A modular genetic switch that tightly regulates gene expression in mammalian ... they combined repression at a lactose operon (lac) and a tet-controlled promoter with RNA interference as a means ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a ...

The genome contains tens of thousands of genes. Like a gigantic orchestra, their interaction is the basis for all vital ...