Scientists have characterized the role of thousands of mutations in the BRCA2 cancer gene, findings that may help reassure ...

The difference between hereditary (germline) and acquired (somatic) gene mutations in cancer can lead to much confusion. This is especially true if you’re hearing about genetic testing for a genetic ...

Researchers assessed the association of KRAS mutations in metastatic PDAC with the clinical outcomes and responses to first-line chemotherapy regimens.

Eligibility for treatment with the latest cancer drugs is often determined by genetic mutations in tumors, criteria that ...

The Ras–MAPK (mitogen-activated protein kinase) pathway is another important cell-proliferation pathway downstream of EGFR that is frequently activated in cancer. Although mutations in Ras ...

After an allogeneic stem cell transplant, a recipient’s body faces a daunting task: rebuilding the person’s blood-forming and ...

A genetic fault long believed to drive the development of esophageal cancer may in fact play a protective role early in the disease. This unexpected discovery could help doctors identify which ...

Yale researchers are sifting through a mosaic of cells in a living animal—both normal cells and mutated cells—to better ...

Scientists have analyzed thousands of mutations in the BRCA2 cancer gene, offering crucial insights. This research could help mitigate patient concerns or guide tailored treatments. By utilizing ...

A surprising discovery reveals that a gene previously thought to accelerate esophageal cancer actually helps protect against it initially. This pivotal study could lead to better prediction and ...

Cancer grows from mutations in a person’s cells. Parasites are separate organisms that live on or in another host organism.

There's no doubt lung cancer has a genetic component. You can inherit genetic mutations (alterations in your genes) that increase your risk for lung cancer. However, you acquire most mutations during ...