Research papers focused on the importance of LNP structures and injection route in developing better LNP non-viral gene therapies for autoimmune diseases and metabolic disorders, such as diabetes.

Significant diversity in lipid structure exists, with between 1000 and 2000 different lipid species thought ... As such, it requires a near constant source of metabolites to maintain function. The ...

Lipids play roles in energy storage, signalling and as structural components. Two studies published in Nature report the structure of apolipoprotein B100 on LDL using high-resolution, artificial ...

HANGZHOU, China--(BUSINESS WIRE)--HighField Biopharmaceuticals, a clinical stage company using lipid-based therapeutics to treat cancer and other diseases, announced today publication of two ...

Stable CDL binding is accommodated by a largely degenerate protein fold that combines interactions from distant basic residues with greater intercalation of the lipid within the protein structure.

Department of Chemical Engineering, Northeastern University, Boston, Massachusetts 02115, United States ...

The evolution of the basic structure of the Constitution began in 1950 when the progressive impulses of the national movement came into conflict with a conservative judiciary. The striking down of the ...

Ron Ofri, DVM, PhD, DECVO, provided veterinary professionals at the Veterinary Meeting & Expo conference ways to make ophthalmic exams less intimidating for general practitioners ...

Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

The UN General Assembly (UNGA) is the main policy-making organ of the Organization. Comprising all Member States, it provides a unique forum for multilateral discussion of the full spectrum of ...

Florida has a Republican triplex. The Republican Party controls the offices of governor, secretary of state, and attorney general. Attorneys general are elected to four-year terms in federal midterm ...