This highlights the importance of genetic background in pharmacological ... when designing experiments and interpreting results in mouse model research[4]. Phenotype: The observable physical ...
Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the ... regardless of the genetic mutation causing their disease.
Medical genetics involves the application of genetics ... administration of AAV9-SUMF1 gene therapy in the Sumf1-KO mouse model of Multiple Sulfatase Deficiency. They show that it provides ...
More information: Meirui An et al, In vivo base editing extends lifespan of a humanized mouse model of prion disease, Nature Medicine (2025). DOI: 10.1038/s41591-024-03466-w . www.nature.com ...
Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...