Scientists in China have engineered embryonic stem cells to produce lab mice with two male parents. Though these mice reached adulthood with developmental issues, the method offers insights into ...
CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...
Continue reading about off-target effects in this story. Base and Prime Editing Offer Precision CRISPR-based systems that rely on traditional Cas nucleases like Cas9 cut through both strands of DNA ...
Scientists have developed a simple, cheaper genome editing method that can be used on many insects, raising hopes for applying the technology to produce more edible bugs. A group of researchers ...
Prime editing has gained recognition as a highly precise genome editing method, often outperforming other Cas9-based techniques. We recently introduced innovative nCas9-DNA polymerase fusion proteins ...
To overcome these limitations, the scientific community has been actively pursuing genome editing methods that are faster, more cost-effective, and less reliant on complex cultivation practices.