Peptides have gained significant attention in research due to their possible role in regulating various physiological ...

The search items we used were keywords “growth hormone insensitivity”, “IGF-I”, “GH receptor”, “mutations of GH receptor”, and “therapy with IGF-I”. We also searched the ...

email:c.brook{at}ucl.ac.uk BACKGROUND Growth hormone insufficiency (GHI) is diagnosed conventionally by short stature and slow growth, and is confirmed by diminished peak GH response to a provocation ...

Characterization of a novel alternatively-spliced 5' exon in the human insulin-like growth factor I (IGF-I) gene, expressed in liver and some cancers. Insulin-like growth factor-1 directly ...

MVR reduces blood flow, which can lead to cerebral ischemic disease. Reduced availability of certain hormones and growth factors, including growth hormone, IGF-1, and vascular endothelial growth ...

Quantifying the hormone itself is not sufficient to detect exogenous rhGH. More stable serum variables implied in the biological cascade produced by hGH secretion, or a doping application, may be the ...

Background: As people age, circulating levels of insulin-like growth factors (IGFs) and IGF binding protein 3 (IGFBP-3) decline. In rat cardiomyocytes, IGF-I has been shown to regulate sarcolemmal ...

But as the years went on, he began to notice his body changing in unusual ways: His head grew so much that he needed a larger helmet, and his hands became so big he had to have his wedding ring ...