pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems and play a role in BCC. The requirement ...

One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Aggressive prostate cancer (PCa) variants ...

Innovative therapies revive a once-undruggable mitochondrial aging regulator through a revolutionary enzyme activation ...

This study presents a valuable finding on a potential signaling pathway responsible for the direct effects of nicotine on intestinal stem cell growth and tumorigenesis. The evidence supporting the ...

A study by researchers at Wayne State University links exposure to air pollution to an increased risk of type 2 diabetes.

Learn why your sleep habits may signal underlying depression, how extended bed rest affects mental health, and steps toward ...

Impact and progress Frontiers' impact Progress Report 2022 All progress reports ...