Title ” The PAQR-2 and HIF-1 pathways are physiologically essential for unsaturated fatty acid homeostasis in C. elegans ” Opponent Professor Jennifer Watts, School of Molecular Biosciences, ...

1 Department ... of signal transduction mechanisms and gene regulation involved in immune responses has created opportunities for the discovery of novel therapeutic compounds useful in treating ...

A reduced number of master signalling pathways operate during development, acting repeatedly at different moments and regions in the embryo and eliciting diverse cellular responses. This raises the ...

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The three-signal paradigm tries to capture how the innate immune system instructs adaptive immune responses in three well-defined actions: (1) presentation of antigenic peptides in the context of MHC ...

Recent advances in genomics and proteomics have identified a large number of molecules and signaling pathways that potentially promote or limit diseases such ... molecules may reduce optical signals ...

Second, chemotherapy can act as a radiosensitizer, improving the probability of local control and, in some cases, survival, by aiding the destruction of radioresistant clones ( Table 1).

(F) Isolated ISCs were cultured in a medium with or without 1 nM Ingenol-3-angelate and 1 μM MK-0752 (3 wells/group). (G) Schematic model of NIC-associated signaling pathway in ISCs. The model traces ...