In COVID-19 and HIV infection, total count of natural killer cells, B cells, CD4+ T cells, regulatory T cells, memory T and B cells decrease, whereas the count of follicular helper cells increase.

HIV infection leads to a phenomenon of inflammaging, in which chronic inflammation induces an immune aged phenotype, even in individuals on combined antiretroviral therapy (cART) with undetectable ...

A key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T cell. Dysregulated CD4 T cells have been implicated in autoimmune liver disease ...

10, 2024 — A newer vaccine against hepatitis B virus was clearly superior to an older vaccine type in inducing a protective antibody response among people living with HIV who didn't respond to prior ...

Pseudoscience has recently re-emerged in the U.S. While much of it concerns vaccines, an "oldie" is again making the rounds: ...

Human immunodeficiency virus type 1 (HIV-1) targets important cells of our immune system, making infected individuals more vulnerable to diseases and infections. Once inside human cells ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

All lymph node biopsy samples were stained for CD19 (pan B-cell marker), CD20 (pan B-cell marker), CD138 (plasma cells), CD23 (follicular dendritic cells (FDCs)), PD-1 (follicular T helper cells, TFH) ...

Stages of HIV Infection The stages of infection from person to person vary slightly, both in severity and the speed of progression. These stages map the depletion of CD4 T-cells and other evidence of ...