"What is a tumor?" This is the fundamental question to answer if we want to treat cancer effectively. Our vision of cancer ...

ongoing immune response, and overall survival. A customized immunogram was created to identify important immunological characteristics. Kyoto Encyclopedia of Genes and Genomes and Hallmark pathway ...

A team led by the Cancer Immunogenomics group at the Josep Carreras Leukaemia Research Institute, the Computational Biology group at the Barcelona Supercomputing Center and the Germans Trias i Pujol ...

The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress ...

A team led by the Cancer Immunogenomics group at the Josep Carreras Leukaemia Research Institute, the Computational Biology group at the Barcelona Supercomputing Center and the Germans Trias i Pujol ...

Since the application of molecular biology in cancer ... microenvironment of supporting cells including stromal cells, such as lung fibroblasts, and tissue resident and transient circulating ...

according to its hallmark’s expression instead of cell-type. In this way, they could see how malignant cells specialised in growing the tumour, while non-cancer cells surrounding it – called the ...