Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

2 Department of Hepatobiliary Surgery, St James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, UK Correspondence to Professor Mark Hull, Leeds Institute of Molecular Medicine, ...

As for the amount of protein required for microarray analysis, we usually request 100-200 µl containing 0.5-1.0 mg of protein per ml of a stable buffered solution (for example Hepes buffered saline) ...