This important manuscript proposes a new strategy for the identification of new mechanisms of drug resistance based on SAturated Transposon Analysis in Yeast (SATAY), a powerful transposon sequencing ...

Post-translational modification generally refers to the addition of a functional group covalently to a protein as in phosphorylation ... blockade of KDM2A, a histone 3 demethylase, in skeletal ...

Given that the role of PRMT1 in metabolic regulation has been well-documented, we then investigated whether PRMT1 is involved in transforming 6133 cells through metabolic reprogramming. To assess this ...

The other regulatory mechanism identified to date is the signal-mediated phosphorylation of adaptor proteins such as RssB and McsB. Phosphorylation. An alternative mechanism used to regulate ...

This course provides an introduction to the various epigenetic mechanisms, an updated presentation of novel aspect of epigenetic ... analysis of modified bases in DNA and RNA and histone modifications ...