Thousands of metabolic pathways exist and most involve multiple steps – some can be hundreds of steps long! All metabolic pathways together form a complex network that is necessary to maintain life.

The approach was applied to the sialic acid metabolic pathway in human cells, yielding novel mutants with phenotypes related to the inborn metabolic defect sialuria and metastatic tumor cells.

All metabolic pathways have to be regulated and controlled to stop the build-up of an end product that isn’t needed. The cell can control a metabolic pathway by the presence or absence of a ...

For example, bacteria have a rigid cell wall, whereas human cells are surrounded ... or MEP pathway for short. The MEP pathway is an essential part of the energy metabolism of several bacteria ...

The new molecules target a metabolic pathway that only occurs in bacterial cells, thus sparing human cells. The team published its results in the journal Angewandte Chemie International Edition.

This prompted Long to explore its metabolic pathways and he homed in on an understudied taurine metabolite called N-acetyltaurine. 1 Long’s fascination with metabolism stems from its role in how the ...

Gut bacteria-produced exopolysaccharides (EPS) help regulate metabolism by modulating gut microbiota, promoting SCFA ...

Genetic variants of the receptors involved in the metabolic pathway lead to anomalies in the human skeleton. "In fact, a new drug, vosoritide, has recently been developed that acts on the cGMP ...