Intranasal foralumab can modulate a number of immune cell types in people with non-active SPMS, developer Tiziana Life ...

Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.

In this study, the function of JAKs in DCs was investigated with tofacitinib. Methods The effects of tofacitinib on the maturation of human monocyte-derived DCs induced by lipopolysaccharide (LPS) ...

Here we use pharmacologic, genetic, human, and in vivo models to systematically detail that this well-established reduction in oxidative phosphorylation is unexpectedly dispensable for the induction ...

suggesting increased potential to form multinucleated cells compared with non-classical monocytes. Interestingly, increased DC-STAMP expression has also been noted in human non-classical CD16 + ...

Discover how atopic dermatitis, an allergic skin condition characterised by inflammation and heightened IgE levels, is often ...

During the COVID-19 pandemic, health worker Maria Tereza Malheiros Sapienza's curiosity was aroused by her immunity to ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Jan. 24, 2025 — A new study shows that long-read sequencing has the potential to improve the rate of diagnosis while reducing the time to diagnosis from years to days -- in a single test and at ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

January 24, 2025 New Once Human codes have been added to the list. What are the latest Once Human codes? There are times in all of our gaming lives when we need a little bit of help. Call it a ...