Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of ...

Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

A parasitic worm infection, also known as a helminth infection, occurs when parasitic worms, or helminths, infect the body.

Monocytopenia describes a low number of monocytes, a type of white blood cell. Monocytes are made in the bone marrow and account for 2% to 6% of white blood cells at any given time. They work ...

Targeting macrophage polarization and the ensuing macrophage-induced inflammation could ... Macrophages are cells of the innate immune system and belong to the large family of mononuclear phagocytes.

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical studies have implicated macrophage-mediated immune tolerance. Hence, pathways ...

TJ and IC performed experiments and analysed data. CJM, MV and JvdG performed experiments. EW contributed to flow cytometry experimental design and measurements. SSR collected human tissue samples and ...

Here we use pharmacologic, genetic, human, and in vivo models to systematically detail that this well-established reduction in oxidative phosphorylation is unexpectedly dispensable for the induction ...

Gen Alpha is about to have some competition. Babies born from January 1st are part of Generation Beta, a label for those born from 2025 to 2039. The research firm McCrindle said in a blog post that ...

They have conjured dramatic scenarios, like AI-driven extinction of humans (and many other species), or our assimilation into human-AI cyborgs. The predictions are generally grim, pitting the fate of ...