Each human cell contains 23 pairs of chromosomes that carry DNA within their nucleus. The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair.

Researchers at the Francis Crick Institute studying male mice engineered with different Y chromosome deletions have uncovered which genes on the mouse Y chromosome regulate the development of ...

The human Y chromosome, responsible for determining male sex, has been gradually shrinking over millions of years. This phenomenon raises intriguing questions about the future of human evolution ...

A study conducted by a research team at the Crick Institute identified important genes on the Y chromosome that regulate sperm development and male fertility. Using thirteen mouse models, the ...

Female mammals typically carry two X chromosomes — one from each parent — and a new study suggests that the maternal X is ...

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don’t ...

Human genetics is complex ... The final pair are sex chromosomes, which scientists label X and Y. The Y chromosome is associated with the development of male sex characteristics.

plays a critical role in the disintegration of the Y chromosome, linking LOY to genomic instability and aging processes. LOY in human male cells was first identified over 60 years ago but gained ...