It has been estimated that the human immune system can produce up to 1 quintillion different antibodies by changing the sequence of these amino acids, helping to ensure that the body can respond to a ...

Antibodies with similar amino acid sequences, especially across their complementary-determining regions, often share properties. Finding that an antibody of interest has a similar sequence to ...

The study, led by assistant project scientist Takeya Masubuchi, revealed several previously unknown PD-1 characteristics, including a “motif” — a specific sequence of amino acids — that is ...

It has been estimated that the human immune system can produce up to 1 quintillion different antibodies by changing the sequence of these amino acids, helping to ensure that the body can respond ...

select a candidate TCR for cloning and use it to construct a TCR transgenic mouse. The argument is that this process is less cumbersome than the classical approach, which involves the identification ...

BCR and antibody-derived libraries, respectively. Demultiplexing of the raw sequencing data was done using bcl2fastq2 (v2.20). Mapping of the gene expression data to the mouse genome (GRCm38; ensembl ...

Monoclonal antibodies (mAb) and antibody-drug conjugates (ADCs) are widely used biological therapeutics. A key property of these biologics is the extent and rate of internalization into different ...

Flow cytometers, microscopes, and fluorescence readers are important for the inspection of cell analysis. In aligned, consumables circumscribe antibodies, sequencing kits, PCR reagents, embedding ...