This barricade prevents water from breaking the peptide bonds through a process called hydrolysis. "We provide evidence that that interaction prevents water from attacking the peptide bonds and ...

This interaction involves the sharing of electrons between neighboring peptide bonds, which keeps water molecules from ...

This generally occurs through protease-mediated hydrolysis of peptide bonds, but can also occur through non-enzymatic methods such as by action of mineral acids and heat.

Proteases are enzymes that catalyse hydrolysis of the peptide and isopeptide bonds that join amino acids within proteins (known as proteolysis). Proteases can also remove protein post ...