T-cell lymphoma is a type of lymphatic cancer that starts in the T lymphocytes (T cells), a type of white blood cell. T lymphocytes (T cells) and B lymphocytes (B cells) are two types of white blood ...

Chimeric antigen receptor (CAR)-T cells and T-cell therapies have been used in the treatment of various cancers for several years. In a review published in JAMA, a research team led by Christian ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

promotes regulatory T cell (Treg) development by activating the Aldh1a2/Raldh2 gene in dendritic cells through the aryl hydrocarbon receptor (AhR) and PU.1/IRF4 pathways. Raldh2, encoded by the ...

Regulatory T (T Reg) cells are essential for maintaining peripheral tolerance, preventing autoimmunity and limiting chronic inflammatory diseases. However, they also limit beneficial responses by ...

CD4 T helper cells are a type of white blood cell called a lymphocyte that serves an important role in your immune system. These cells help defend the body against infection by directing other "killer ...

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

Besides T cells, B cells are now considered important contributors to the pathogenesis of T1D, according to recent studies. In non-obese diabetic (NOD) mice, the absence of B cells prevents the ...

There’s been huge progress in treatments for blood cancer in recent years – but drawbacks of expensive CAR-T cell and injected ... drivers including MYC and IRF4. The 26 patients treated ...

Uncover the scientific processes that cause hair to lose its color, from genetic influence to lifestyle factors, and learn ...

In a recent study, researchers have identified that kaempferol, a flavonoid, produces an anti-inflammatory effect through regulatory T-cell development. This occurred through increased RADLH2 ...

This retinoic acid then promotes the development of regulatory T-cells ... Mediated and PU.1/IRF4‐Dependent Transactivation of the Aldh1a2/Raldh2 Gene in Dendritic Cells, Allergy (2024).