To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on their surfaces. This protein, called the ...
The evolution of robust and flexible defense responses has been driven by the diverse and adaptive nature of foreign threats. To maintain its effectiveness, the immune system produces highly ...
These newly recognized platelet functions, including the secretion of immune mediators, interactions with endothelial cells, monocytes, and neutrophils, toll-like receptor (TLR) mediated responses, ...
In addition, it can deplete regulatory T cells, thereby overriding their antitumour immune responses. Anthracyclines can induce an immunogenic variant of apoptosis in tumour cells, thereby ...
Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...
Lymphoid tissues in the upper respiratory tract contain immune cells that are crucial for local immunity. An analysis of adenoid tissue from individuals during and after SARS-CoV-2 infection is ...
Design Glutathione peroxidase 4 (GPx4), which is considered the master regulator of ferroptosis, was genetically altered in murine models for hepatocellular carcinoma (HCC) and colorectal cancer (CRC) ...
The immune deficiency disorder occurs when certain types of white blood cells, known as histiocytes ... but we can't do it without the lifesavers that sign up to our register.