To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on their surfaces. This protein, called the ...

The PRIMER cells expressed a new transcription factor—a type of protein that regulates gene expression—called GT-3a, which is likely an important upstream alarm for alerting other cells to an ...

Cancer cells can poison attacking immune cells by filling them with defective mitochondria ― dampening the body’s defensive forces and helping the tumour to evade eradication 1. These findings ...

The evolution of robust and flexible defense responses has been driven by the diverse and adaptive nature of foreign threats. To maintain its effectiveness, the immune system produces highly ...

The team discovered a unique population of immune cells that is important to the successful treatment of relapsed acute myeloid leukemia (AML). This investigation was done in partnership with the ...

A new discovery in blood immune cells has put researchers one step closer to identifying a blood biomarker that would allow doctors to personalize treatments for Parkinson's disease. In a multi ...

Scientists have created a new atlas of plant cells during immune response, in turn discovering a new rare cell state, called Primary IMmunE Responder (PRIMER), that acts as an immune response hub ...

Their study in mice found that during periods of low energy— such as intermittent fasting—ILC2 immune cells step in to regulate blood sugar levels, acting as a “postman” in a previously ...

The cells, called c-kit+IL-17A+ ILC2s, can be likened to chameleons; they can change their characteristics and have traits of two different types of immune cells.

The goal of the transplant is to replace the patient’s hematopoietic stem cells – cells that rejuvenate supplies of blood and immune cells – with donor stem cells that are not cancerous. In addition, ...

Chameleon-like immune cells could be contributing to severe asthma. The cells can shift between two types of immune cells ...