To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on their surfaces. This protein, called the ...

Whether the protocol described here can be further optimized in terms of cytokine concentrations or inclusion of other immune cell activating cytokines such as IL-4, IL-18 and IL-21, used in several ...

Following T cell commitment, developing T cells undergo multiple selection checkpoints by engaging with the extracellular matrix, and interacting with thymic epithelial cells (TECs) and other immune ...

In addition, it can deplete regulatory T cells, thereby overriding their antitumour immune responses. Anthracyclines can induce an immunogenic variant of apoptosis in tumour cells, thereby ...

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

January 2025 If you haven’t looked at what your cell phone bill might be under a new plan or on a new service, you should check now. In recent years prices have come down and data allocations ...

Jan. 30, 2025 — A new study has highlighted the potential of resveratrol, a natural compound found in grapes, blueberries, and raspberries, to enhance female fertility. The systematic review ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Narrow focus: Performance-based goals can cause us to neglect important demands of our work or life that aren't specified in the ... of our brain called the habenula, often referred to as the ...

After hours: January 31 at 7:49:57 PM EST Loading Chart for ACIU ...