CAR-T treatments begin by taking some of the patient’s own T cells. T cells are part of the body’s immune system and are involved in detecting and destroying infected or cancerous cells.

Stress resulting from prolonged exposure to aversive stimuli may cause hyperactivity of lateral habenula neurons and immune responses in the medial habenula. These responses may lead to a general ...

To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on their surfaces. This protein, called the ...

These cells deal with microbes and repair tissue damage. Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular ...

But a study published yesterday (September 15) in Nature Cell Biology suggests that an interaction between T cells and antigen presenting cells (APCs) early in the immune response to viruses may ...

Scientists have discovered that T cells -- white blood cells that can ... Their findings reshape our understanding of how our immune system works, paving the way for the design of more effective ...

This "targeting system" is an artificial protein called a chimeric antigen receptor (CAR) that helps immune cells recognize and attack cancer cells. While current CAR T-cell therapies require ...

A research team has revealed a previously unknown mechanism that triggers an inflammatory immune response ... types of injury, cells release the IL-1α protein. It doesn't act on the cell itself ...

Scientists in the laboratory of Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of ...

Cases of secondary tumors have been reported as a possible adverse reaction to the treatment of certain blood cancers with CAR T-cells. A recent analysis of the cases reported to the ...