It has been shown in rats that silibinin protects neonatal hepatocytes from cell damage produced by erythromycin, amitriptyline, nortriptyline and TBH. [21] The cytoprotective activity of ...

Our mission is to provide a state-of-the-art facility, expertise, and education in advanced quantitative light microscopy to support Drexel University’s research community The Cell Imaging Center (CIC ...

This important study provides insights into the physiological role of RIPK1 in liver physiology, particularly during short-term fasting. The discovery that RIPK1 deficiency sensitizes the liver to ...

ACCIDENTAL HOST—The Story of Rat Lungworm Disease reveals the frightening spread of a foodborne parasite that invades human brains and now thrives in tropical areas of five continents ...

Through the use of hepatocyte-specific Ripk1-deficient mice (Ripk1Δhep), the authors embarked on an examination of the consequences of Ripk1 deficiency in hepatocytes under fasting conditions. They ...

A MASH-inducing diet caused DNA damage in the liver cells (hepatocytes) of MUP-uPA mice. This triggered the DNA-damage response (DDR; a signalling pathway that repairs DNA damage and limits the ...

exclaimed another, highlighting the sheer size of the unwelcome visitors. A video of the giant rats was shared on the @sydneynameandshame Instagram page. Picture: Instagram Some commenters pointed ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Expression of the receptor RAGE in biliary ...

To understand the intricate cellular and epigenetic changes occurring within this critical zone, we utilized single-cell assay for transposase-accessible chromatin sequencing (scATAC-seq) to profile ...

Rats are consuming drugs that were seized and stored by Houston police and hundreds of cases could be vulnerable to the rodent infestation, officials said. It's an issue that has prompted the ...

Here, we describe the contribution of hepatocyte ferroptosis to CD8 + T cell activation in a model of primary HCC and metastatic colon cancer and identify the complex interaction between cancer, ...