Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Patisiran ...

4 To identify complex inherited diseases associated with a peripheral neuropathy, we compiled the authors’ lists and performed a PubMed search (in September 2016) for all publications describing a ...

Long-term treatment with patisiran (Onpattro) led to modest changes for people with hereditary transthyretin amyloidosis (hATTR) with polyneuropathy, data from a global open-label extension (OLE ...

The most common form of inherited peripheral neuropathy results from overexpression of a single gene. Simple application of an antiprogesterone drug can reduce gene expression and alleviate ...

In the longest study of an RNAi therapeutic for any disease, patisiran treatment demonstrated modest improvements in patients with hereditary transthyretin-mediated amyloidosis with polyneuropathy ...

Polyneuropathy occurs when multiple peripheral nerves become damaged. Symptoms include problems with sensation, coordination, or other body functions. Polyneuropathy is also known as peripheral ...

WES was performed on the longitudinally collected DNA samples from diverse inherited polyneuropathy subjects. Comprehensive bioinformatics review of the obtained exomes is also carried out to address ...

Intellia doses the first patient in the phase III HAELO study on NTLA-2002 for treating hereditary angioedema. Stock rises.

There are differences in handling a spousal Inherited Roth 401(k) versus an inherited Traditional 401(k). When you have a Roth 401(K), you likely will need to address the Roth savings and the 401 ...

Hereditary ATTR amyloidosis: burden of illness and diagnostic challenges. Amer J Manag Care. 2017;23(7):S0. González‐Duarte A, Conceição I, Amass L, Botteman MF, Carter JA, Stewart M. Impact of ...