The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team.

Announcing a new article publication for BIO Integration journal.   Diabetes, a common metabolic condition, poses a substantial health burden worldwide. To revolutionize diabetes management, enhance ...

G-protein coupled receptors regulate hormone secretions in ... levels that stems from the decreased secretion and/or action of insulin. Two major forms of diabetes exist, type 1 and type 2.

and mice with a fat-specific insulin-receptor deficiency are also long-lived. Lipophilic hormones, including steroids, also modulate ageing in worms and flies. Related lipophilic hormones are ...

Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) acts as a negative regulator of the insulin signaling pathway by dephosphorylating both the insulin receptor (IR) and the insulin receptor ...