Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

The stiffness of the extracellular matrix (ECM), which is governed by the content and crosslinking of ECM proteins ... and CD49f), which in turn promotes BCSC survival and proliferation.

Background—Laminin receptors are involved in cell-extracellular matrix interactions in malignant cells that show invasion and metastasis ... Methods—The expression of several laminin receptors, ...

Transgenic mouse models of Marfan syndrome exposed a surprising and crucial function of elastic extracellular matrix components in regulating TGFβ signalling. By interacting with unprocessed ...

Researchers currently use extracts from the basement membrane, a specific type of extracellular matrix, to culture organoids ... Joost J.A.P.M. Wijnakker et al, Integrin-activating Yersinia ...

Aberrant expressions of matrix proteins by cancer-associated fibroblasts (CAFs) alter the mechanical properties of the tumor extracellular matrix (ECM). This results in increased ECM desmoplasia and ...

CRASH-2 trial collaborators, Lancet, 376:23-32, 2010. 3. Focus on focal adhesions » The architecture of focal adhesions—structures that mediate signaling and adhesion to the extracellular matrix—is ...

Department of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Respiratory Health, Frontiers Science Center for Disease-related ...