Besides an extensive range of genetic and epigenetic alterations, components of the tumor microenvironment tend to exert a significant impact on tumor progression. The so-called tumor ...

This combination therapy showed significant tumor growth delay and improved survival rates in preclinical models, suggesting that integrin-targeted imaging can play a role in optimizing ...

Integrins are very attractive therapeutic targets in oncology. The anti-tumor mechanisms of integrin-targeting drugs have been validated both in vitroand in vivo. Integrin-targeting drugs are ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including milk thistle, turmeric, and green tea, that target the tumor ...

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...