Iron-overload diseases result from inappropriate iron acquisition in response to iron need. Excess iron can damage tissue, cause fibrosis and give rise to organ failure. Iron-deficiency disorders ...
Iron overload is a common and severe complication in both TDT and NTDT patients due to increased intestinal iron absorption and regular transfusions. The excess iron accumulates in vital organs ...
[2]G. Asare, M. Kew et al. “Effects of Exogenous Antioxidants on Dietary Iron Overload.” Journal of clinical biochemistry and nutrition (2008). 85 - 94.
This iron overload triggered ferroptosis and tissue damage. Critically, when they treated the mice with drugs that inhibit ferroptosis or mop up iron, I/R injury was less severe 4. The same set of ...
Discover top medications for 'treating Hemochromatosis (Iron Overload)'? This page compiles essential information on generic and brand-name drugs specifically used for Hemochromatosis (Iron ...
A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...