The endocrine cells confined in the islets of Langerhans are responsible for the maintenance of blood glucose homeostasis. In particular, beta cells produce and secrete insulin, an essential hormone ...

COUR Pharmaceuticals, a clinical-stage biotechnology company developing first-in-class, disease-modifying therapies designed ...

Langerhans cell histiocytosis (LCH) is a disease caused by clonal expansion of CD1a+/CD207+ cells and is characterized by organ involvement and dysfunction. Treatment of LCH in children is ...

In a first-in-human study at the ATMP center at Uppsala University Hospital in Sweden, the world’s first transplantation of genetically modified, hypoimmune insulin-producing cells from the islets of ...

Glucagon is secreted to the blood by alpha cells located in the pancreatic islet of Langerhans, the authors explained. “Fasting or high energy–consumption sports activities can result in low ...

Dar es Salaam. Zanzibar President Hussein Mwinyi on Monday gave investors holding leases for undeveloped islets three months to commence construction or risk losing their rights. The directive comes ...

Three people with type 1 diabetes who received Vertex Pharma’s islet cell therapy VX-880 have been able to come off insulin altogether within a year, raising the prospect of a life without ...

For people with severe type 1 diabetes, transplantation of islets of Langerhans containing insulin-producing cells has been an established treatment for over 20 years. These cells come from the ...

This study provides compelling evidence for functional subpopulations of β-cells responsible for Ca2+ signal initiation and maintenance using novel three-dimensional light sheet microscopy imaging and ...

For several years, Lena Eliasson's research group has explored mechanisms that regulate insulin secretion from beta cells situated in the islets of Langerhans within the pancreas. Together with ...