Creating cancer therapies based around natural killer cells could offer similar levels of efficacy to CAR-T therapies, but at around one hundredth of the cost. Researchers at MD Anderson Cancer ...
Cytokine-induced killer cells are a heterogeneous cell population that can be expanded ex vivo ... These cytokines can improve cell proliferation and cytotoxicity partly by suppressing the generation ...
Conclusions: Our study shows clear differences in the intrahepatic expression of ICMs on NK cells and T cells in chronic HBV patients depending on their clinical stage. Hepatitis B is one of the most ...
Freshly isolated NK cells, but not natural killer T cells or ordinary T cells, from the liver expressed cell surface TRAIL, which was responsible for spontaneous cytotoxicity against TRAIL ...
When infused into mice, T cells grown with DCA lived much longer compared to those grown in traditional culture media. Almost one year later, over 5% of circulating killer T cells were those that had ...
A study shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer. Investigators examined how molecular dynamics at the immune synapse ...
Bone-marrow-derived multipotent progenitor stromal cells — or mesenchymal stem cells (MSCs) — are the common predecessors of cells of the mesenchymal lineage, such as bone, cartilage and fat ...
1Masonic Cancer Center, Minneapolis, Minnesota. 6Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota. 7Department of ...
An investigational induced pluripotent stem cell-derived CAR natural killer cell therapy was well ... who had received previous autologous CAR T-cell therapy, an area of continued unmet need ...