Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by a near-total absence of ...

the effects of too little leptin are widespread (including infertility, impaired immune function, decreased insulin response and altered homeostasis). Although leptin mutations are not common in ...

Discover how tirzepatide, a diabetes drug, offers hope for congenital generalized lipodystrophy (CGL) treatment, potentially ...

a distinct circadian pattern for plasma leptin concentrations has been observed and is similar to that of prolactin and thyroid stimulating hormone. 1 Conflicting evidence implicates insulin as a ...

The first patient, a 23-year-old man who had refused the painful daily treatments with leptin and insulin for 2 years, saw his average blood glucose drop from 252 to 128 milligrams per deciliter ...

especially in people with insulin resistance or type 2 diabetes. Leptin, often called the "satiety hormone," is produced by fat cells and helps regulate energy balance by inhibiting hunger.

A weekly diabetes medication may replace painful daily hormone injections for patients with congenital generalised lipodystrophy (CGL). Early findings suggest that tirzepatide – used for diabetes and ...

A weekly injection of diabetes medication could replace painful daily hormone shots for patients with a rare form of lipodystrophy.

Serum levels of insulin and leptin, BMI and abdominal obesity were compared in 200 men with benign prostatic hyperplasia (BPH) scheduled to undergo surgery and 302 controls. [13] Abdominal obesity ...

Adequate sleep helps balance hunger hormones, preventing overeating and aiding weight management. Regular physical activity boosts metabolism, enhances fat burning, and builds muscle for higher ...