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DNA 聚合酶在 DNA 复制过程中发挥着关键作用，其主要形成磷酸二酯键，以确保遗传信息的准确传递。同时，这一过程还涉及到多种相关的化学反应和酶的协同作用。 1. 磷酸二酯键的形成机制：DNA 聚合酶通过催化脱氧核苷酸之间的反应，将一个脱氧核苷酸的 5'磷酸基团与另一个脱氧核苷酸的 3'羟基相连，从而形成磷酸二酯键。这是 DNA 链延长的基础。 2. 对 ...

DNA nanotechnology is a branch of nanotechnology concerned with the design, study and application of synthetic structures based on DNA. DNA nanotechnology takes advantage of the physical and ...

Cdk activity drives cell-cycle progression as far as metaphase, but progression into anaphase and beyond depends on another major regulatory component — a ubiquitin-protein ligase called the ...

The replication crisis in psychology refers to concerns about the credibility of findings in psychological science. The term, which originated in the early 2010s, denotes that findings in ...

Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible over time, a process that is termed glucose toxicity. Our perspective about glucose toxicity as it ...