Preserving levels of brain glucose metabolism can both slow cognitive decline and reduces the risk of conversion to dementia.

Prostate cancer is the most common non-cutaneous cancer in men in the United States. Cancer metabolism has emerged as a contemporary topic of great interest for improved mechanistic understanding of ...

The article provides an overview of the current understanding of the interplay between metabolic pathways and immune function in the context of triple-negative breast cancer (TNBC). It highlights ...

Conclusion Oxidative stress, especially through purine metabolism pathway, is a major metabolic event during reperfusion and may contribute to the ischaemia reperfusion injury of lung grafts. Data are ...

A new technology is poised to transform the discovery of microbial species and enzymes with specific in situ metabolic functions. The technology, FISH-scRACS-seq (Fluorescence In Situ ...

The MEP pathway is an essential part of the energy metabolism of several bacteria, including the hospital germ Pseudomonas aeruginosa. If the MEP pathway in bacteria is blocked, for example by a ...

Objective The extent to which tryptophan (Trp) metabolism alterations explain or influence the outcome of inflammatory bowel diseases (IBDs) is still unclear. However, several Trp metabolism ...

By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic ...

Objectives To investigate the effect of the L-arginine metabolism on arthritis and inflammation-mediated bone loss. Methods L-arginine was applied to three arthritis models (collagen-induced arthritis ...

The new molecules target a metabolic pathway that only occurs in bacterial cells, thus sparing human cells. The team published its results in the journal Angewandte Chemie International Edition.