Metabolic disorders such as iron overload, glycolysis, insulin resistance, lipid dysregulation, and glutaminolysis are found to induce liver senescence and ferroptosis, which are hot topics in the ...

Scientists at Michigan Medicine have made a significant breakthrough in treating nonalcoholic fatty liver disease (NAFLD), a ...

Fatty liver disease, the excessive lipid accumulation in the liver, is a frequent metabolic condition that can progress in cancer. Despite years of research, targeted treatments are still lacking and ...

Here, we experimentally examined diet-microbe- host interactions through a complex systems framework, centered on dietary oxalate. Using multiple, independent molecular, animal, and in vitro ...

"The glycolytic enzyme aldolase is essential for liver cancer cells, although the glycolytic pathway itself is apparently dispensable," says metabolism expert Schulze, summarizing the findings.

Glucose is metabolized to acetyl CoA through the standard glucose metabolic pathway. Acetyl CoA is then carboxylated by acetyl CoA carboxylase ... While TAG synthesis can take place in the brain, ...

The study links exertional heat stroke to chronic disorders, revealing impacts on body mass regulation and heart health, ...

As well as finding a credit-card sized amount of the tiny plastic bits in human brains, scientists discovered the volume has ...

Researchers from Kumamoto University have identified a liver-derived protein, serine protease inhibitor A1 (SerpinA1), as a key regulator in combating obesity and enhancing glucose metabolism.

A new technology is poised to transform the discovery of microbial species and enzymes with specific in situ metabolic functions. The technology, FISH-scRACS-seq (Fluorescence In Situ ...