We report the specific gene expression profile induced by leptin in white adipose tissue and liver. From these analyses, it is possible, for the first time, to distinguish leptin treatment from ...

brown adipose tissue (BAT) burns it, generating heat. As people age, BAT diminishes, increasing obesity risk. SerpinA1, a hepatokine secreted by the liver, has been shown to reverse this process ...

Metabolic dysfunction-associated steatotic liver disease, or MASLD, is an umbrella term describing conditions related to a ...

Little is known about epigenetic alterations associated with subcutaneous adipose tissue (SAT ... harmful fat depots (intra-abdominal and liver fat) also correlated with measures of insulin ...

When metabolic endotoxemia was induced for 4 weeks in mice through continuous subcutaneous infusion of LPS, fasted glycemia and insulinemia and whole-body, liver, and adipose tissue weight gain ...

CIRM awards US$ 4 mn grant to Entos Pharma to advance development of ENTLEP001, a durable and redosable genetic medicine to treat CGL: San Diego Friday, February 7, 2025, 15:00 Hr ...

The liver and pancreas are the main actors in glucose metabolism, but not the only ones. Muscles, adipose tissue and the brain play different roles. However, the prize for the best new actor in ...

Why do we need to talk about fat? Because adipose tissue is an endocrine organ and as such a prominent signaling hub for maintaining metabolic health of our entire body! Immune cells populating the ...

Our recent work suggested that BA overload in mice genetically deficient for the nuclear receptor FXR and SHP (double knockout, DKO) results in unexpected beneficial anti-obesity and anti-diabetes ...

Inventiva (IVA) announced the publication in Journal of Hepatology, a peer-reviewed scientific journal, of the results from the ...