We report the specific gene expression profile induced by leptin in white adipose tissue and liver. From these analyses, it is possible, for the first time, to distinguish leptin treatment from ...

While resident adipose tissue macrophages display an anti-inflammatory phenotype and promote the development ... As the NADPH oxidase catalytic subunit, NOX2 has been demonstrated to be involved in ...

Metabolic dysfunction-associated steatotic liver disease, or MASLD, is an umbrella term describing conditions related to a ...

Accumulating evidence reveals that adipose tissue is an immunologically active organ that exerts multiple impacts on the regulation of systemic energy metabolism. Adipose tissue immunity is modulated ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

brown adipose tissue (BAT) burns it, generating heat. As people age, BAT diminishes, increasing obesity risk. SerpinA1, a hepatokine secreted by the liver, has been shown to reverse this process ...

Inventiva (IVA) announced the publication in Journal of Hepatology, a peer-reviewed scientific journal, of the results from the ...

The liver and pancreas are the main actors in glucose metabolism, but not the only ones. Muscles, adipose tissue and the brain play different roles. However, the prize for the best new actor in ...

When metabolic endotoxemia was induced for 4 weeks in mice through continuous subcutaneous infusion of LPS, fasted glycemia and insulinemia and whole-body, liver, and adipose tissue weight gain ...

Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by a near-total absence of ...