Genes can produce more than one messenger RNA (mRNA ... so to better capture these, we also used long-read sequencing that reads between 5,000 and 30,000 base pairs at a time and does not ...

This is partly because current clinical testing uses a method called short-read sequencing, which cannot access information in certain regions of the genome and so may miss crucial evidence to help ...

Now, a group of researchers present data that suggests that long-read sequencing may be the better road to go down for these people. The more comprehensive dataset can find variation, eliminate ...

We integrated high-throughput single-cell 3’-RNA-sequencing with targeted Iso-Seq long-read RNA sequencing on the PacBio Sequel II platform to overlay single-cell genotype with cell-type and gene ...

We focus primarily on human medical genetics. Our portfolio includes multiple short-read-based applications from whole transcriptome to small RNA sequencing. We also offer long-read RNA sequencing on ...

Principle of Nanopore Sequencing: DNA/RNA is passed through protein nanopores embedded in a non-conductive polymer ... allowing for the determination of the DNA sequence. PacBio's long read lengths ...

The researchers investigated and compared several sequencing approaches, including short- and long-read sequencing of cDNA that they generated from the mRNA vaccine and direct RNA sequencing with long ...

Next-generation sequencing (often noted as NGS), describes the high-throughput technologies that can now determine the sequence of a given nucleic acid strand, such as DNA or RNA, in a matter of hours ...

Samples are commonly stored in a way that degrades RNA. Scientists are devising new ways to overcome this obstacle for RNA sequencing. RNA is more subject to degradation than ... and paraffin-embedded ...