Alveolar macrophages (AMs) are critical components of the innate defense mechanism in the lung. Nestled tightly within the alveoli, AMs, derived from the yolk-sac or bone marrow, can phagocytose ...

However, in the mouse model of kidney injury, S100a4 was found to be co-expressed with macrophage antigens Mac1, Mac2, and Mac3 as well as CD45 and CD68 (11). Similar findings were reported in renal ...

Feb. 6, 2025 — Despite new medication, cystic fibrosis often leads to permanent lung damage. Researchers have discovered that the disease causes changes in the immune system early in life ...

Lung diseases are some of the most common medical conditions in the world. Tens of millions of people have lung disease in the U.S. alone. Smoking, infections, and genes cause most lung diseases.

Objective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented.

Lung cancer liver metastases are tumors that form in the liver from cancer cells that have broken away from the primary cancer and spread through the blood or lymphatic system. The liver is a common ...

The gold standard for finding lung cancer early is computed tomography (CT) lung cancer screening. However, this is limited to people who have smoked. Currently, there are more non-smokers (never ...

The iron lung, conceptualized in the late 1920s, was most notably the first line of defense against polio during the epidemics that occurred between 1948 to 1955. The device saved the lives of ...

The underlying regulatory mechanisms of metabolic switching are assessed by both in vitro and in vivo studies. Conclusions Selectively modulating the ‘context’ of glycolytic macrophages in HCC tumours ...

In some cases, you may have lung granulomas that show no abnormal signs. They don’t usually need treatment or other testing. Granulomas are usually found during a doctor’s visit for something ...