Autophagy is a highly conserved catabolic process that involves an intracellular degradation system in which cytoplasmic components, such as protein aggregates, organelles, and other macromolecules, ...

Magnified perinuclear regions (right) are indicated by yellow boxes ... Small, filled dots indicate the origin (0 μm) in distance. Supplementary Fig. 1. Endosomes and lysosomes form giant structures ...

Along trafficking from the PM to the perinuclear area, the equipment of channels and transporters of the vesicle ... (2020) have recently demonstrated that lysosomes rapidly swell in response to a ...

perinuclear localization of the SCV and manipulation of the microtubule and actin networks around the SCV. Salmonellae are important causes of enteric diseases in all vertebrates. Characterization ...

Missense mutations that derail SORL1 trafficking cause AD. Other variants shift AD risk in East Asians and Europeans. SORL1 dysfunction messes with endosomes in neurons, and with lysosomes in ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Macrophages are the primary cells responsible for nanoparticle processing and ...

† Median OS not reached at 21 months for eight patients with primary PCL. CE: Cyclophosphamide, etoposide; dex: Dexamethasone; M-80: Intermediate-dose melphalan, dexamethasone; MP: Melphalan ...