近日，美国得克萨斯大学西南医学中心Yunsun Nam团队揭示了癌症相关突变如何通过改变METTL3-METTL14复合体对RNA甲基化（m6A）的特异性来促进肿瘤发生。研究发现，METTL14的R298P突变能够改变m6A的序列偏好，优先修饰含有GGAU ...

3.2 The role of m6A methylation readers in liver cancer immunotherapy The immune microenvironment of HCC is composed of a complex network of tumor cells, immune cells, and stromal elements, all of ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...

Given the crucial role of RNA m 6 A methylation in various biological processes ... Reference: Zhou L, Gao G, Tang R, et al. Redox modification of m6A demethylase SlALKBH2 in tomato regulates fruit ...

This valuable study provides integrated analyses of RNA sequencing and mapping data of the m6A RNA modification in the context of unbalanced genomes, using aneuploid Drosophila as a model, and ...

Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing 100875, China Key Laboratory of Cell Proliferation and Regulation ...